Introduction
As people's living standards continue to improve, pet dogs are becoming increasingly important in the family. More and more people regard dogs as close companions and family members and give them undivided love and care. However, in modern life, dogs also face various pressures and challenges and may suffer from emotional problems such as anxiety and tension.
On the one hand, changes in the living environment are one of the common causes of emotional problems in dogs. For example, situations such as job changes of the owner and relocation of the family may make the dog feel uneasy. New environments, unfamiliar people and other animals may trigger fear and anxiety in dogs. In addition, noises in daily life, such as the sound of car horns and firecrackers, may also frighten the dog and create nervousness.
On the other hand, a dog's own physical condition may also affect its mood. For example, some dogs may suffer from diseases or be in special physiological stages, such as illness and estrus, etc. Dogs are more prone to mood swings in these situations. At the same time, differences in a dog's personality can also lead to different levels of emotional response. Some dogs are naturally more timid and sensitive, and are more likely to be affected by external factors and become anxious.
Anxiety and nervousness in dogs can not only affect their health and quality of life, but also cause distress to their owners. Anxious dogs may have behavioral problems such as excessive barking, destroying objects, and defecating, affecting the harmonious atmosphere of the family. In addition, dogs that are chronically anxious may also face health risks such as decreased immunity and digestive disorders.
Therefore, finding effective calming supplements for dogs has become an urgent need for many pet owners. These supplements can help dogs relieve anxiety and stay calm, thus improving their quality of life and giving owners more peace of mind. There are a variety of dog calming supplements available on the market today, but they vary in effectiveness and safety. Next, we will conduct in-depth research and analysis of these supplements to provide pet owners with scientific advice on choosing them.
Classification |
Details |
The Impact of Dogs' Emotional Problems |
On dogs' health: It leads to loss of appetite, sleep disorders and weakened immunity. On owners' lives: It causes behaviors such as destroying furniture and excessive barking, disrupting the harmony of family life. |
The Role of Calming Supplements |
Relieve dogs' emotional problems and improve their behaviors, making them calmer, more docile and obedient. |
Classification and Characteristics of Common Calming Supplements - Based on Ingredients |
Natural ingredients: Such as magnesium-containing ingredients (for example, Healthspan MagiCalm for Dogs, which can relax muscles and relieve tension), and aloe vera ingredients (have the effects of soothing the skin, relieving itching and calming). Synthetic ingredients: Act quickly and have accurate dosage, but may have side effects. |
Classification and Characteristics of Common Calming Supplements - Based on Action Mechanisms |
Those that regulate the nervous system: Achieve calming effects by influencing the secretion of neurotransmitters; those that relieve stress: Realize calming by reducing dogs' stress responses with specific plant extracts. |
Evaluation Criteria for Effectiveness - Safety |
No harm to dogs' health, no allergies, poisoning and other situations, and in line with relevant standards for pet food and health products. |
Evaluation Criteria for Effectiveness - Efficacy |
Significant practical effects, reflected in relieving emotions and improving behaviors, and the calming effect lasts for a reasonable time. |
Evaluation Criteria for Effectiveness - Palatability |
Dogs are willing to accept it and it does not affect their normal appetite. |
Research Results Summary |
Sort out common classifications, evaluation criteria and effective product cases. |
Suggestions for Pet Owners |
Choose suitable products according to dogs' age, weight and personality, and control the usage and dosage according to the instructions. |
Future Research Directions |
Develop new products that are safer and more effective, and dig deeper into the action mechanisms of different ingredients. |
Common Dog Sedation Supplements
There are a wide variety of dog calming supplements on the market today, all of which are designed to help dogs relieve anxiety, stay calm, and improve their quality of life. The main types of common dog calming supplements are listed below:
1. Cannabidiol (CBD)
Cannabidiol, a non-psychotropic phytocannabinoid found in marijuana, is increasingly being explored as an alternative to traditional therapies for the treatment of health problems in dogs and cats. In companion animals, CBD appears to have good bioavailability and safety, with few side effects at physiologic doses. CBD has been found in some canine studies to improve clinical signs of osteoarthritis, pruritus, and epilepsy, and may also have a role in reducing anxiety and decreasing aggression in dogs and cats.
However, there is limited data on the efficacy and long-term safety of CBD. The quality of CBD supplements available on the market for pets varies, with misleading terminology or untested advertising, unregulated manufacturing, lower than labeled CBD levels and/or higher than permissible limits of tetrahydrocannabinol. To legally market CBD products, they must first be approved by the U.S. Food and Drug Administration (FDA), but there is currently a lack of clear regulatory guidance from the FDA because cannabis and its derivatives are not explicitly defined as food additives by AAFCO and CBD is not considered a GRAS.
2. Probiotics
3. Nutritional Supplements
Biotin and Fish Oil: Biotin is essential for normal growth and body function in animals, helping with the body's metabolism, conversion of carbohydrates, fats, and proteins into energy, absorption and utilization of other B vitamins by the body, and helping the body to remove protein by-products. Biotin plays a very important role in maintaining healthy skin and coat in dogs and cats. Increasing the intake of biotin can help improve symptoms such as dry, lackluster coat, hair loss, brittle nails, eczema, and seborrheic dermatitis. Fish oil contains omega-3 fatty acids, which can improve the quality of the dog's coat, make the coat shiny, and can relieve the dog's skin allergies.
Glucosamine, Chondroitin Sulfate, etc.: Glucosamine is an aminosugar found naturally in the fluids around canine joints to aid in cartilage health. Many veterinarians believe that glucosamine can be an effective treatment for arthritis in dogs and, in older dogs, can relieve joint pain and improve mobility. A study of a nutritional supplement showed that the commercial supplement Dynamopet srl (consisting of glucosamine sulfate, Krill oil, chondroitin sulfate, black prong, Krill flour, shiitake mushrooms, askanthera, and a product obtained through herbal conversion, among others) was beneficial for animal welfare, improving joints, and alleviating pain in dogs with osteoarthritis, and that the different ingredients included in the supplement may work through different mechanisms of action to Improvement of the inflammatory state and oxidative stress in cellular health.
4. Pet Calming Formulations
A pet calming formula represents a carefully concocted blend of diverse elements, each playing a distinct yet complementary role in promoting a sense of tranquility among our furry friends. At its core are ingredients like cedarwood oil, which has been revered for centuries for its soothing properties. Derived from the cedar tree, this essential oil emits a woody, earthy aroma that has a profound impact on a pet's olfactory senses. When inhaled, it seems to trigger a relaxation response, harkening back to the natural, calming scents of the forest that might instinctively put an animal at ease.
Sodium lauryl sulfate, although often associated with detergents and surfactants in industrial applications, in the context of a pet calming formula, serves a specific purpose. In minute and carefully regulated amounts, it aids in the dispersion and stability of the other components, ensuring that the formula functions optimally when applied or diffused. This helps to create a consistent and effective delivery of the calming agents, allowing the formula to work its magic over time.
The fragrance oils incorporated into the mix add an additional layer of olfactory allure. These are often crafted to be both pleasant to human noses – as pet owners are also in proximity to the treated products – and highly appealing to pets. They work in tandem with the natural plant extracts, such as lemongrass oil, rosemary oil, or peppermint oil. Lemongrass oil, for instance, with its citrusy and herbaceous notes, has a refreshing quality that can distract a pet from anxiety-inducing stimuli and induce a state of calm. Rosemary oil, with its rich, resinous aroma, is believed to have mild sedative effects, while peppermint oil provides a cooling sensation that can soothe frayed nerves, making it an ideal ingredient for pets that might be agitated due to heat or stress.
Water, the universal solvent, forms the base of this formula, facilitating the combination and dilution of the other ingredients to achieve the right potency. Through the process of evaporation, the active components are released into the air or onto the surface of pet products like diaper pads and pet houses. As the formula slowly dissipates, the calming scents permeate the immediate environment, creating a serene atmosphere that envelops the pet. This passive exposure to the soothing blend allows the pet to gradually relax, reducing hyperactivity, excessive barking, or nervous pacing.
To summarize, the world of dog calming supplements is as diverse as the canine population itself. Different formulations, with their unique ingredients and corresponding mechanisms of action, offer a plethora of options for pet owners seeking to address their dog's anxiety or restlessness. However, this variety can also be overwhelming. It's of utmost importance that pet owners don't make hasty decisions based on anecdotal evidence or marketing claims. Consulting professional veterinarians is the wisest course of action. Veterinarians, armed with in-depth knowledge of a dog's physiology, potential allergies, and existing health conditions, can provide tailored advice. Based on a dog's specific situation – be it age, breed predispositions to anxiety, or recent changes in its living environment – they can guide owners towards choosing a calming supplement that is not only effective in promoting calmness but also completely safe, free from any potential adverse reactions that could compromise the dog's well-being. This way, pet owners can ensure that their beloved companions enjoy a peaceful, stress-free life, strengthening the bond between human and animal through proper care and attention.
The Importance of Sedation Supplements for Dogs
Emotional problems such as anxiety and nervousness in dogs may lead to loss of appetite, sleep disorders, decreased immunity and other health problems. When a dog is in a state of anxiety, its body produces a range of physiological responses. For example, anxiety may affect a dog's digestive system, causing a loss of appetite that may lead to malnutrition in the long run. Sleep is also vital to your dog's health, and anxiety may interfere with your dog's sleep, leading to sleep disorders. Lack of sleep can affect both your dog's physical and mental state, further weakening its immunity. Additionally, chronic anxiety can trigger other health problems such as endocrine disorders.
Emotional problems in dogs can also cause distress to their owners, such as destroying furniture, excessive barking and other behaviors that affect the harmony of family life. Dogs may vent their emotions by destroying furniture when they are anxious or nervous. This will not only cause financial loss to the owner, but also spoil the tidiness and beauty of the home. Excessive barking is also one of the common manifestations of emotional problems in dogs, which can affect the neighbors and bother the owner. In addition, the dog's emotional problems may also affect the owner's mood and quality of life, making the family atmosphere tense.
Classification and Characteristics of Common Dog Sedation Supplements
1.Classification Based on Ingredients
(1) The Role and Advantages of Magnesium Ingredients
Magnesium is a normal cellular component that is essential for many biochemical reactions. For dogs, magnesium ingredient has an important role in dog calming supplements. Adult dogs require 11mg of magnesium per kilogram of body weight per day, puppies 22mg per kilogram of body weight per day, and pregnant and lactating dogs have a 2-fold higher magnesium requirement. Magnesium helps to relax muscles, relieve tension, and more. For example, when the dog is anxious, magnesium can participate in the reaction of energy metabolism, maintain the normal function of the heart and skeletal muscle and nerve tissue, regulate the balance between calcium and magnesium, thus helping the dog to relieve anxiety.
(2) The Efficacy of Aloe Vera Ingredients
(3) Synthetic Ingredient Sedation Supplements
Synthetic ingredient sedative supplements are characterized by rapid action and accurate dosage. For example, Valium, chlorpromazine and phenobarbital (or isoamylbarbital) are commonly used in clinical practice, of which Valium is the most commonly used and safest. The method of administration can be intramuscular or oral, intravenous push or slow intravenous drip, but these drugs have the possibility of causing allergic reactions, and some drugs such as carbamylcholine can also cause low blood pressure or even shock, so care must be taken when using. The dosage varies depending on the breed, age, physical condition of the dog, and the drug dosage form. Also, if benzodiazepines are used, they should only be used in puppies and small dogs, as adult dogs have developed resistance to this class of drugs. However, synthetic ingredients sedative supplements may have certain side effects, and long-term use may result in physical dependence and mental dependence, as well as possible damage to the dog's liver and other organs. Therefore, such drugs can only be used temporarily to relieve symptoms, and should not be taken in large quantities for a long period of time.
2.Classification Based on the Mechanism of Action
(1) Sedative Supplements to Regulate the Nervous System
The nervous system of the dog plays a vital role in its mood and behavior. Sedative supplements that regulate the nervous system mainly affect the secretion of neurotransmitters to achieve the effect of sedation. For example, some supplements contain ingredients that regulate the levels of neurotransmitters such as serotonin. Serotonin is a neurotransmitter associated with mood stabilization, sleep cycles, and decision-making, and by increasing serotonin levels, you can help your dog relieve anxiety and stay calm. Additionally, some supplements may affect the secretion and action of other neurotransmitters that regulate your dog's nervous system function. These supplements may contain specific plant extracts, amino acids, or other bioactive ingredients that work to regulate your dog's mood by binding to receptors in the nervous system or by participating in nerve signaling processes.
(2) Sedative Supplements for Stress Relief
Sedative supplements whose primary mechanism of action is stress relief usually contain products with specific plant extracts that achieve sedation by reducing the dog's stress response. For example, some supplements contain L-theanine, an amino acid most commonly found in the plants used to make green tea and long administered for its sedative effects.L-theanine can help stabilize mood and has a much lower risk of toxicity or adverse effects than some other sedative ingredients. It reduces stress and anxiety in dogs by binding to glutamate receptors and preventing the brain from becoming overly excited. In addition, some plant extracts such as lavender extract are widely used in dog calming supplements. Lavender has soothing and relaxing properties that help dogs reduce their stress response and stay calm. These supplements achieve their calming effect by regulating your dog's body's response to stress, such as lowering the production of stress hormones and regulating the excitability of the nervous system.
Judging Criteria for Effective Dog Sedation Supplements
1. Safety
Ensure that the calming supplement does not cause adverse effects on your dog's body such as allergic reactions, poisoning, etc. Effective dog calming supplements should first and foremost ensure that they are not harmful to your dog's health. Different dogs may react differently to specific ingredients, for example, some dogs may have an allergic reaction to certain synthetic ingredients in sedation supplements. An allergic reaction may manifest itself in the form of itchy skin, redness, swelling, vomiting, diarrhea, and other symptoms. If your dog develops these symptoms, stop using the supplement immediately and consult your veterinarian for advice. Additionally, some sedative supplements can lead to poisoning if not used properly. For example, certain dogs may be poisoned by accidentally ingesting too much of a sedative supplement and develop serious symptoms such as coma and convulsions. Therefore, when pet owners use sedative supplements for their dogs, they must strictly follow the dosage and usage instructions to avoid any harm to their dogs' health due to improper use.
The product should comply with national or regional standards for pet food and health care products. As a type of pet food and healthcare product, dog calming supplements must comply with relevant national or regional standards. These standards usually include requirements on product ingredients, quality, safety and other aspects. Products that meet the standards can ensure their quality and safety, allowing pet owners to use them for their dogs with greater confidence. For example, some countries or regions have clear regulations on the content of ingredients, microbial indicators, heavy metal content, etc. in pet food and health products. Manufacturers must strictly follow these standards to ensure the quality and safety of their products. At the same time, the relevant departments will also supervise and inspect the pet food and health care products in the market, and take down products that do not meet the standards to protect the rights and interests of consumers.
2.Effectiveness
Case studies are used to demonstrate the actual effects of effective sedative supplements in relieving emotional problems and improving behavior in dogs. Many pet owners have provided feedback that after using Purina Crown Energy prescription food supplements containing specific probiotics, their dogs' anxious behaviors were significantly reduced. For example, some dogs that were hyper-vigilant, barking and pacing became calmer and more relaxed after using the supplement consistently for a period of time. Other dogs have experienced reduced tension and more relaxed muscles after using calming supplements that contain natural ingredients such as magnesium. In some cases, a dog's anxiety due to environmental changes or external stimuli has been improved by the use of calming supplements that regulate the nervous system. For example, supplements containing specific plant extracts that can regulate the levels of neurotransmitters such as serotonin make dogs less overly fearful and nervous when faced with new environments or noises, and more stable in their behavior.
The cross-border hot-selling pet calming chewable tablets have also received favorable reviews from many pet owners. Some dogs have experienced improved sleep quality, reduced anxiety symptoms, and less disruption to their owners' lives after using the chewable tablets.Mighty Petz MAX Dog Calming Chewable Tablets for Dogs contain a variety of soothing ingredients, such as hemp seed powder and oil, passionflower, and valerian root, to provide daily anxiety relief in a tasty way. Many pet owners report that their dogs are receptive to these chewables and show gentler behaviors such as less hyperactivity and aggression after use.
The calming effect should be of some duration, rather than a short-lived effect. Recovery time after sedation in dogs varies depending on the breed, age, and physical condition of the dog, as well as the type and dosage of sedative used. Generally, the effects of tranquilizers in dogs begin to wear off within a few hours, but a full return to normalcy may take longer. For example, some dogs are able to remain calm for several hours after using a calming supplement, which can be very helpful in dealing with specific stressful situations such as traveling, visiting the veterinarian, or experiencing noise stimulation. However, the duration varies from supplement to supplement. Some calming supplements with natural ingredients may last for a relatively short period of time and need to be used more frequently, while some calming supplements with synthetic ingredients may last for a longer period of time, but may carry the risk of side effects. Therefore, pet owners need to consider factors such as duration and safety when choosing sedative supplements.
3. Palatability
Considering your dog's taste preference is crucial in choosing a sedative supplement. Dogs have a very keen sense of smell and taste, and they have high requirements for the taste of food and medications. If a sedative supplement does not taste good, the dog is likely to refuse to consume it. Therefore, when choosing a sedative supplement, pet owners should focus on the taste of the product. Some sedative supplements with natural ingredients, such as those containing magnesium or aloe vera, may have a relatively milder flavor that is more easily accepted by dogs. For some sedative supplements with synthetic ingredients, the taste may need to be improved by adding some special flavorings to improve the dog's acceptance.
Sedation supplements should not affect your dog's normal appetite, which may lead to malnutrition and other problems. Some sedative supplements may have some effect on your dog's digestive system, thus affecting their appetite. For example, some sedative supplements with synthetic ingredients may cause adverse reactions such as nausea and vomiting in dogs, which in turn can lead to a loss of appetite. On the other hand, sedative supplements with natural ingredients are relatively safer and have less impact on your dog's appetite. For example, calming supplements containing probiotics, such as Purina Crown Energy Prescription Food Supplement, can not only help keep your dog calm, but also promote intestinal health, with no adverse effects on your dog's appetite. In addition, pet owners should also pay attention to the changes in their dog's appetite when using sedation supplements for their dogs, and should consult their veterinarian for advice on adjusting their medication regimen if they notice a decrease in appetite or other conditions.


Future Research Directions
As the research on sedative supplements for dogs continues to deepen, future research directions can be carried out in the following areas:
1.Developing New Products That Are Safer and More Effective
Although the sedative supplements for dogs currently on the market can relieve dogs' anxiety to a certain extent, there are still some problems, such as the risk of side effects that may exist in some of the supplements with synthetic ingredients, and the effect of supplements with natural ingredients may not be significant enough. Therefore, the development of safer and more effective new products is one of the important directions for future research.
Conduct more in-depth research on existing natural ingredients such as magnesium and aloe vera to clarify their mechanism of action in dogs. For example, further explore how magnesium ingredients participate in the energy metabolism reaction in dogs and how to more precisely regulate the balance between calcium and magnesium in order to better exert its calming effect.
Investigate whether there are other potential benefits in the aloe vera component beyond its known anti-inflammatory sedative and antibacterial antipruritic effects. Also, look for ways to reduce the adverse effects of saponins and aloe-vera glycosides in aloe vera on dogs and improve the safety of aloe vera consumption in dogs.
Look for more natural ingredients from nature that have calming effects. New calming supplement ingredients for dogs can be discovered by screening and researching various plants, minerals, and more. For example, some traditional Chinese herbs may have potential calming effects and can be researched and developed.
Study the synergistic effect between different natural ingredients. A judicious combination of multiple natural ingredients may produce better calming effects, while reducing the amount of a single ingredient used and the risk of potential side effects.
For sedative supplements with synthetic ingredients, such as Valium, Chlorpromazine and Phenobarbital, which are commonly used in clinical practice, their formulations and production processes should be further optimized to reduce the risk of side effects. For example, by improving the molecular structure of the drugs, their targeting and safety can be enhanced, and damage to organs such as the liver of dogs can be reduced.
To study how to reduce the somatic dependence and mental dependence of sedative supplements with synthetic ingredients. This can be done by adjusting the dosage and duration of use of the drugs, as well as developing new complementary therapies to reduce the dog's dependence on the drugs.
2.In-depth Study of the Mechanism of Action of Different Ingredients
It is now known that the ingredients in some supplements can regulate the level of serotonin and other neurotransmitters, thus helping dogs to relieve anxiety. In the future, the role of different neurotransmitters in dog anxiety can be further investigated, as well as how to more precisely regulate the secretion and action of these neurotransmitters.
Explore the interactions between other neurotransmitters and serotonin. For example, to study the synergistic effects of neurotransmitters such as dopamine and norepinephrine with serotonin in regulating mood in dogs, and to provide a theoretical basis for the development of more effective sedative supplements.
For sedative supplements with stress relief as the main mechanism of action, such as products containing L-theanine and lavender extract, in-depth studies should be conducted on how they reduce the stress response in dogs. The relationship between these ingredients and stress hormones, nervous system excitability, etc. in dogs can be studied at the molecular level.
Study the differences in the mechanism of action of different plant extracts in relieving stress in dogs. By comparing the chemical composition and biological activities of different plant extracts, the most effective ingredients and formulations can be identified to provide reference for the development of new sedative supplements.
Many calming supplements for dogs may act through multiple mechanisms simultaneously, and future research should synthesize the interrelationships between these mechanisms. For example, some supplements can regulate the function of the nervous system as well as alleviate the stress response. Studying the synergistic effect between these two mechanisms of action will help develop more comprehensive and effective sedative products.
Combine the physiological characteristics and behavioral features of dogs to study the changes in the mechanism of action of sedative supplements in different situations. For example, the mechanism of action of sedation supplements may be different when dogs are in different physiological stages and facing different environmental stimuli, and understanding these changes can provide the basis for individualized treatment plans.
In conclusion, future research on sedative supplements for dogs should be devoted to the development of safer and more effective new products, and in-depth study of the mechanism of action of different ingredients, so as to provide pet owners with more and better choices to help their dogs relieve anxiety and improve their quality of life.
Frequently Asked Questions
Q&A Section
Question 1: Why do pet owners need to find an effective calming supplement for dogs?
A: On the one hand, dogs are prone to anxiety and nervousness in situations such as thunderstorms, being alone, being in unfamiliar environments, etc. This can lead to a loss of appetite, poor sleep, and lowered immunity, which affects the dog's own health. On the other hand, this kind of emotion triggers excessive barking, destroying furniture and other undesirable behaviors, which brings trouble to the owner's daily life, so pet owners are in urgent need of effective dog calming supplements.
Question 2: What are the advantages of natural ingredients in dog calming supplements, and what are some examples of their representative ingredients?
A: The advantages of natural calming supplements for dogs are that they are safer, gentler, and reduce the risk of side effects, which is in line with pet owners' expectations for health care. Take magnesium as an example (e.g. Healthspan MagiCalm for Dogs contains magnesium), it helps to relax the dog's muscles, relieving the body's tension due to nervousness, which in turn relieves the overall nervousness; Aloe Vera not only calms the dog, but also soothes the skin and reduces the itching sensation, so the dog can benefit both physiologically and psychologically from the relief of external discomforts to the smoothness of the mood. The aloe vera ingredient not only calms the dog, but also soothes the skin and reduces itching.
Question 3: What are the key criteria for determining the effectiveness of a calming supplement for dogs?
A: There are three key criteria. Safety, to ensure that there is no harm to the dog's health, such as not triggering allergies, poisoning, etc., and strictly in line with the national or regional pet food, health care products related standards. Effectiveness level, need to have a significant effect in the actual application, can effectively relieve the dog anxiety, tension, improve such as barking, restlessness and other undesirable behaviors, and sedative effect to maintain a reasonable length of time, not fleeting. Palatability is also extremely important, the product flavor should be accepted by the dog, willing to take the initiative to eat, and at the same time should not interfere with the dog's normal appetite to avoid causing malnutrition and other subsequent problems.
Question 4: Taking Healthspan MagiCalm for Dogs as an example, how does it show that it is an effective calming supplement for dogs?
A: From the product introduction, it has clear labeling of ingredients and efficacy, and is suitable for specific dog breeds and age groups, providing a basis for rational use. In the user evaluation, in terms of calming effect, there are many feedbacks that it can make the dog, which is originally easy to be frightened and anxious, more emotionally stable when facing the daily stimulation sources (such as the sound of firecrackers); in terms of palatability, the dog is not resistant to consuming it; and in terms of safety, there are no adverse reactions to it when used in accordance with the instructions. Effectiveness analysis combined with examples, such as the separation of severe anxiety of the dog, insist on using a period of time, alone when the destructive behavior is reduced, rest more stable, comprehensive proof of its effectiveness.
Question 5: For pet owners to choose dog calming supplements, what are the expected future research directions to help?
A: There are two main research directions to look forward to in the future. The first is to develop new types of products, focusing on safer and more efficient features, such as the combination of new ingredients from natural plants, minerals and other resources, and the use of advanced biotechnology to optimize the formulation, reduce the risk of potential side effects and enhance the calming effect. Second, in-depth study of the mechanism of action of different ingredients, some of the current ingredients are known to have a calming effect, but the specific neurological and endocrine systems in dogs how to accurately play a regulating effect is still unclear, a detailed analysis can guide the precise selection of products and personalized customized supplements, to meet the special needs of different dogs.